Efficacy of pipelle as a tool for endometrial biopsy

The study concluded that the Pipelle device is a limited endometrial sampling technique for obtaining an adequate and representative endometrial sample. It should be reserved for those patients in whom there is only a minimal risk for endometrial carcinoma, hyperplasia and polyps. Any failure to obtain an endometrial specimen would suggest performing a full endometrial curettage is adviseable, especially in high risk patients for endometrial cancer.

In Lahor between January and December , a study was carried out on patients with abnormal uterine bleeding to assess the efficacy of the Pipelle as a tool for endometrial biopsy. These patients were scheduled for hysterectomies and they had endometrial sampling with the Pipelle before the surgery.

Among patients, 66 underwent hysterectomies. The finding of the final histopathologies were compared with those of the Pipelle.

Of the remaining, six had inadequate specimens, and 28 were postponed for medical reasons. In 61 out of 66 patients, the histology results were identical correlation of The Pipelle was unable to detect one case of endometrial cancer, and labeled it as complex hyperplasia due to the focal nature of malignancy, or the tumour present in an endometrial polyp.

However, hysteroscopy examinations of high risk patients is emphasised, as certain lesions in the endometrium can be missed with Pipelle endometrial sampling. In Shabihkhani hospital in Kashan, Iran, between September to September , a study was done to test the diagnostic value of endometrial sampling with Pipelle in patients with abnormal uterine bleeding.

The study was included patients. Endometrial sampling was performed in all patients with abnormal uterine bleeding. After completion of the study, pathologist reports were compared between two methods. The reports were the same for the two methods except for two cases. Therefore, a negative biopsy in a symptomatic patient must be followed by fractional curettage or hysteroscopy. Transvaginal ultrasound TVUS and endometrial sampling with Pipelle can safely be used together as the initial investigations in the management of abnormal uterine bleeding.

Thickening of endometrium, especially in postmenopausal women, can be a characteristic feature of endometrial cancer. However, the specificity is low. Results Citations. Tables and Topics from this paper.

Citation Type. Has PDF. Publication Type. More Filters. Journal of mid-life health. Highly Influenced. View 4 excerpts, cites results and background. Background: Endometrial sampling for histopathology is important in the assessment of abnormal uterine bleeding. Endometrial tissue sampling using pipelle versus dilatation and curettage for the assessment of endometrium in patients of perimenopausal and post-menopausal age: a prospective study.

View 1 excerpt, cites background. Histological correlation of pipelle endometrial sampling with dilatation and curettage in abnormal uterine bleeding. Aim: To determine frequency of positive endometrial biopsies in pre and post menopausal patients with abnormal uterine bleeding for detection of endometrial carcinoma. The sensitivity, specificity, positive and negative predictive values, and accuracy of pipelle biopsy for endometrial hyperplasia was The P value for endometrial hyperplasia and carcinoma was 0.

Conclusion: Pipelle biopsy is valuable in diagnosing endometrial pathology of AUB cases. It has very high sensitivity and specificity for endometrial malignancies. A hysteroscopic dilatation and curettage is required for definitive diagnosis in cases of polyps and focal endometrial lesions.

Keywords: Abnormal uterine bleeding, endometrial carcinoma, endometrial hyperplasia, hysterectomy, pipelle biopsy. Int J Gynaecol Obstet ; Efficacy of pipelle as a tool for endometrial biopsy. Biomedica ; Shams G. Comparison of pipelle de cornier with conventional dilatation and curettage in terms of patients' acceptability. Is pipelle biopsy really adequate for diagnosing endometrial disease?

Med Sci Monit ;CR Ann King Edward Med Univ ; Evaluation of endometrium in peri-menopausal abnormal uterine bleeding.

J Midlife Health ; Rasheed T, Yasmeen L. Effectiveness of pipelle as endometrial sampling procedure in comparison with dilatation and curettage.